Friday, January 25, 2013

Bioenergy Conservation and Diabetes mellitus

Diabetes mellitus (DM) is related to common metabolic disorders and is expressed by hyperglycemia (i.e. elevated level of glucose in blood). There are a variety of DM and are caused by complex interactions of genetics and environmental factors. In fact DM is a sort of lifestyle associated metabolic disorder. Sedentary lifestyle, over indulgence in alcohol and excessive consumption of fatty fast-food laced with preservatives are the cause of excessive conservation of bioenergy in human body. One should be calorie conscious and take balanced diet to avoid getting obese and over weight. Obesity is an invitation to metabolic disorders.
Non-insulin dependent diabetes mellitus (NIDDM) is also known as diabetes-II (or Type-II Diabetes, where as Diabetes-I is insulin dependant) and is characterized by variable degree of insulin resistance and pancreatic beta cell dysfunction. Loss of metabolic control is probably associated with neuroendocrine control system that effect hepatic glucose output. Computerization and automation in industrial units is the cause of bioenergy conservation in workers, leading to metabolic disorders like diabetes mellitus. Low energy expenditure due to leisure-way lifestyle and reduced sensitivity to peripheral insulin further complicate the case. Vascular complications associated with DM lead to morbidity and mortality in patients with diabetes mellitus. Energy expenditure needs to be increased in diabetics by way of exercise; brisk walking and cycling.  Optimum energy expenditure in diabetics can act as adjunct to reduce the level of hyperglycemia.

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